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Jiande Chen, PhD

Professor of Medicine and Biomedical Engineering, Director, Clinical Gastrointestinal Motility Lab, Johns Hopkins University School of Medicine

Professor of Medicine and Biomedical Engineering, Director, Clinical Gastrointestinal Motility Lab, Johns Hopkins University School of Medicine

Dr. Jiande D. Chen is a professor of medicine at the Johns Hopkins University School of Medicine. He holds a joint appointment in biomedical engineering. Considered the “father of electrogastrography,” Dr. Chen has conducted pioneering research aimed at observing and measuring the stomach’s electrical system.

Dr. Chen received his graduate education at the Catholic University of Leuven in Belgium. While there he started his research on gastrointestinal motility with a group of internationally renowned investigators in the Department of Medicine. Upon completing his PhD in 1989, Dr. Chen moved to the United State where he accepted a faculty position at the University of Virginia, School of Medicine.  In June 1999, he joined the Division of Gastroenterology, Department of Internal Medicine at University of Texas Medical Branch as an Professor and served as Director of Clinical Physiology Lab.

Currently, Dr. Chen is Professor of Medicine in the Division of Gastroenterology and Hepatology at Department of Medicine and Department of Biomedical Engineering at Johns Hopkins University and Director of Clinical Gastrointestinal Motility Lab.

Dr. Chen has received more than 100 research grants (about $17 million) from various government and state agents, such as National Institutes of Health, Veterans Administration, Department of Defense and industries. Dr. Chen has trained more than 80 doctoral students, post-docs and young scholars, filed more than 30 US patents and published more than 360 peer-reviewed papers in leading SCI journals.

Dr.  Chen served as the first President of International Electrogastrography Society and is currently the Vice President of International Gastrointestinal Electrophysiology Society. He served as a council member of American Neurogastroenterology and Motility and board member of North American Neuromodulation Society. He is Associate Editor of Neuromodulation and serves on editorial board for a dozen of international peer-reviewed professional journals.

Dr. Chen’s current research interest is in the area of neuromodulation and its applications for treating obesity, diabetes and functional gastrointestinal diseases and inflammatory bowel diseases. Examples of his research projects include functional gastrointestinal diseases; gastric electrical stimulation for obesity; intestinal electrical stimulation for diabetes; spinal cord stimulation for functional gastrointestinal diseases; vagal nerve stimulation for obesity and sacral nerve stimulation for inflammation.

 

Select Publications

  • Chen, Jiande, and Pankaj Jay Pasricha. “Gastrointestinal electrical stimulation.” U.S. Patent 6,826,428, issued November 30, 2004.
  • Chen, Jiande, and R. W. McCallum. “Electrogastrography: measuremnt, analysis and prospective applications.” Medical and Biological Engineering and Computing 29, no. 4 (1991): 339-350.
  • Chen, Jiande, and Richard W. McCallum. “Gastric slow wave abnormalities in patients with gastroparesis.” American Journal of Gastroenterology 87, no. 4 (1992).
  • Foley, Steve, and Jiande Chen. “Sensor based gastrointestinal electrical stimulation for the treatment of obesity or motility disorders.” U.S. Patent Application 11/091,287, filed March 28, 2005.
  • Chen, Jiande, and Richard W. McCallum. “Gastric slow wave abnormalities in patients with gastroparesis.” American Journal of Gastroenterology 87, no. 4 (1992).
  • Tougas, Gervais, Ervin Y. Eaker, Thomas L. Abell, Hasse Abrahamsson, Michel Boivin, Jiande Chen, Michael P. Hocking et al. “Assessment of gastric emptying using a low fat meal: establishment of international control values.” The American journal of gastroenterology 95, no. 6 (2000): 1456.
  • Chen, Jiande, Joos Vandewalle, Willy Sansen, Gaston Vantrappen, and J. Janssens. “Adaptive method for cancellation of respiratory artefact in electrogastric measurements.” Medical and Biological Engineering and Computing 27, no. 1 (1989): 57-63.